Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

MAP2K4

mitogen-activated protein kinase kinase 4

Summary

Cytogenetic location
17p12
Coordinates
Chromosome 17: 12,020,877–12,143,828 (GRCh38)
Exons
11 exons across 123 kb
Protein
399 amino acids
Also known as
MEK4, JNKK1, PRKMK4, MKK4, MAPKK4, SAPKK1, SKK1, JNKK, SEK1
Previous symbols
SERK1
MANE Select transcript
ENST00000353533.10NM_003010.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads MAP2K4 yet. The test sequences your whole genome, so your data includes it all the same.

How MAP2K4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where MAP2K4 sits. MAP2K4 and 2 genes near it on chromosome 17, from 11,582,353 to 12,582,352.Chromosome 1717p12p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.311.6 Mb11.8 Mb12 Mb12.2 Mb12.4 MbDNAH9: 11,598,457–11,969,748, forward strandDNAH9ZNF18: 11,956,202–11,997,494, reverse strandZNF18MAP2K4: 12,020,877–12,143,828, forward strandMAP2K4Diagram of MAP2K4: 11 exons on the forward strand of chromosome 17Exon 1: 12,020,877–12,021,001, 125 basesExon 2: 12,054,889–12,054,991, 103 basesExon 3: 12,081,356–12,081,530, 175 basesExon 4: 12,095,575–12,095,694, 120 basesExon 5: 12,107,790–12,107,909, 120 basesExon 6: 12,110,375–12,110,426, 52 basesExon 7: 12,113,233–12,113,360, 128 basesExon 8: 12,125,294–12,125,371, 78 basesExon 9: 12,129,139–12,129,287, 149 basesExon 10: 12,139,839–12,139,884, 46 basesExon 11: 12,141,147–12,143,828, 2,682 bases1115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.8 kb of the gene's 123 kb; 1,200 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAP2K4 gene: mitogen-activated protein kinase kinase 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/map2k4

Vancouver

Dante Labs. MAP2K4 gene: mitogen-activated protein kinase kinase 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/map2k4

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test