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Gene

LZTS1

leucine zipper tumor suppressor 1

Summary

Cytogenetic location
8p21.3
Coordinates
Chromosome 8: 20,246,165–20,303,963 (GRCh38)
Exons
4 exons across 57.8 kb
Protein
596 amino acids
Also known as
FEZ1
MANE Select transcript
ENST00000381569.5NM_021020.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads LZTS1 yet. The test sequences your whole genome, so your data includes it all the same.

How LZTS1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where LZTS1 sits. LZTS1 and 5 genes near it on chromosome 8, from 19,775,064 to 20,775,063.Chromosome 88p21.3p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.319.8 Mb20 Mb20.2 Mb20.4 Mb20.6 MbINTS10: 19,817,147–19,857,714, forward strandINTS10LPL: 19,901,717–19,967,653, forward strandLPLSLC18A1: 20,144,186–20,183,206, reverse strandSLC18A1ATP6V1B2: 20,197,323–20,233,400, forward strandATP6V1B2LZTS1: 20,246,165–20,303,963, reverse strandLZTS1: 20,255,055–20,255,279, reverse strandDiagram of LZTS1: 4 exons on the reverse strand of chromosome 8Exon 4: 20,246,165–20,250,363, 4,199 basesExon 3: 20,252,782–20,253,585, 804 basesExon 2: 20,254,837–20,255,315, 479 basesExon 1: 20,303,740–20,303,963, 224 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.7 kb of the gene's 57.8 kb; 1,791 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). LZTS1 gene: leucine zipper tumor suppressor 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/lzts1

Vancouver

Dante Labs. LZTS1 gene: leucine zipper tumor suppressor 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lzts1

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