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Gene

LIF

LIF interleukin 6 family cytokine

Summary

Cytogenetic location
22q12.2
Coordinates
Chromosome 22: 30,240,453–30,246,759 (GRCh38)
Exons
3 exons across 6.3 kb
Protein
202 amino acids
Also known as
CDF, DIA, HILDA
MANE Select transcript
ENST00000249075.4NM_002309.5
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads LIF yet. The test sequences your whole genome, so your data includes it all the same.

How LIF is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 22, with a bracket where LIF sits. LIF and 24 genes near it on chromosome 22, from 29,743,606 to 30,743,605.Chromosome 2222q12.2p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3329.8 Mb30 Mb30.2 Mb30.4 Mb30.6 MbZMAT5: 29,728,138–29,767,084, reverse strandZMAT5UQCR10: 29,767,352–29,770,413, forward strandUQCR10ASCC2: 29,788,044–29,838,304, reverse strandASCC2MTMR3: 29,883,141–30,030,868, forward strandMTMR3HORMAD2: 30,080,444–30,211,427, forward strandHORMAD2LIF: 30,240,453–30,246,759, reverse strandLIFOSM: 30,262,829–30,266,858, reverse strandOSMCASTOR1: 30,285,114–30,289,694, reverse strandCASTOR1: 30,285,238–30,299,482, reverse strandTBC1D10A: 30,291,990–30,326,947, reverse strandTBC1D10ASF3A1: 30,331,988–30,356,919, reverse strandSF3A1CCDC157: 30,356,631–30,378,673, forward strandCCDC157RNF215: 30,368,811–30,421,771, reverse strandRNF215SEC14L2: 30,396,941–30,425,303, forward strandSEC14L2: 30,409,255–30,428,990, forward strandMTFP1: 30,425,623–30,429,058, forward strandMTFP1SEC14L3: 30,447,959–30,472,056, reverse strandSEC14L4: 30,488,890–30,505,725, reverse strandSEC14L4SEC14L6: 30,522,799–30,546,741, reverse strandSEC14L6GAL3ST1: 30,554,632–30,576,210, reverse strandGAL3ST1PES1: 30,576,624–30,607,083, reverse strandPES1TCN2: 30,607,003–30,630,712, forward strandTCN2SLC35E4: 30,635,673–30,669,016, forward strandSLC35E4DUSP18: 30,652,051–30,667,887, reverse strandDUSP18OSBP2: 30,693,782–30,907,824, forward strandOSBP2Diagram of LIF: 3 exons on the reverse strand of chromosome 22Exon 3: 30,240,453–30,244,061, 3,609 basesExon 2: 30,244,755–30,244,933, 179 basesExon 1: 30,246,677–30,246,759, 83 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.9 kb of the gene's 6.3 kb; 609 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). LIF gene: LIF interleukin 6 family cytokine. Retrieved 17 October 2026, from https://dantelabs.com/genes/lif

Vancouver

Dante Labs. LIF gene: LIF interleukin 6 family cytokine [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lif

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