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Gene

LEFTY1

left-right determination factor 1

Summary

Cytogenetic location
1q42.12
Coordinates
Chromosome 1: 225,886,282–225,889,146 (GRCh38)
Exons
4 exons across 2.9 kb
Protein
366 amino acids
Also known as
LEFTYB
Previous symbols
LEFTB
MANE Select transcript
ENST00000272134.5NM_020997.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads LEFTY1 yet. The test sequences your whole genome, so your data includes it all the same.

How LEFTY1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where LEFTY1 sits. LEFTY1 and 15 genes near it on chromosome 1, from 225,387,714 to 226,387,713.Chromosome 11q42.12p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44225.4 Mb225.6 Mb225.8 Mb226 Mb226.2 MbDNAH14: 224,896,262–225,399,292, forward strandDNAH14LBR: 225,400,900–225,428,925, reverse strandLBRENAH: 225,486,765–225,653,334, reverse strandENAHSRP9: 225,777,699–225,790,670, forward strandSRP9EPHX1: 225,810,048–225,845,567, forward strandEPHX1TMEM63A: 225,845,532–225,884,122, reverse strandTMEM63ALEFTY1: 225,886,282–225,889,146, reverse strandLEFTY1: 225,886,696–225,924,278, reverse strandPYCR2: 225,914,982–225,924,340, reverse strandPYCR2LEFTY2: 225,936,598–225,941,532, reverse strandLEFTY2SDE2: 225,982,693–225,999,385, reverse strandSDE2H3-3A: 226,061,571–226,073,207, forward strandH3-3AACBD3: 226,144,679–226,186,763, reverse strandACBD3MIXL1: 226,223,508–226,227,384, forward strandMIXL1LIN9: 226,231,149–226,309,869, reverse strandLIN9PARP1: 226,360,210–226,408,154, reverse strandPARP1Diagram of LEFTY1: 4 exons on the reverse strand of chromosome 1Exon 4: 225,886,282–225,887,090, 809 basesExon 3: 225,887,399–225,887,638, 240 basesExon 2: 225,887,786–225,888,032, 247 basesExon 1: 225,888,817–225,889,146, 330 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 2.9 kb; 1,101 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). LEFTY1 gene: left-right determination factor 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/lefty1

Vancouver

Dante Labs. LEFTY1 gene: left-right determination factor 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lefty1

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