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Gene

KIRREL3

kirre like nephrin family adhesion molecule 3

Summary

Cytogenetic location
11q24.2
Coordinates
Chromosome 11: 126,423,358–127,000,770 (GRCh38)
Exons
17 exons across 577.4 kb
Protein
778 amino acids
Also known as
NEPH2, KIAA1867, KIRRE
MANE Select transcript
ENST00000525144.7NM_032531.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KIRREL3 yet. The test sequences your whole genome, so your data includes it all the same.

How KIRREL3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where KIRREL3 sits. KIRREL3 and 12 genes near it on chromosome 11, from 125,845,945 to 127,578,183.Chromosome 1111q24.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25126 Mb126.2 Mb126.4 Mb126.6 Mb126.8 Mb127 Mb127.2 Mb127.4 MbHYLS1: 125,883,614–125,900,846, forward strandHYLS1PUS3: 125,892,347–125,903,227, reverse strandPUS3DDX25: 125,903,348–125,943,702, forward strandDDX25VSIG10L2: 125,946,044–125,958,647, forward strandVSIG10L2CDON: 125,955,796–126,063,335, reverse strandCDONRPUSD4: 126,201,792–126,211,692, reverse strandSIRAL1: 126,211,687–126,265,162, forward strandSRPRA: 126,255,132–126,269,144, reverse strandSRPRAFOXRED1: 126,269,024–126,281,756, forward strandFOXRED1TIRAP: 126,282,497–126,298,845, forward strandTIRAPDCPS: 126,303,971–126,350,005, forward strandDCPSST3GAL4: 126,354,677–126,442,293, forward strandST3GAL4KIRREL3: 126,423,358–127,000,770, reverse strandKIRREL3Diagram of KIRREL3: 17 exons on the reverse strand of chromosome 11Exon 17: 1 known disease-causing siteExon 17: 126,423,358–126,425,023, 1,666 basesExon 16: 126,425,638–126,425,724, 87 basesExon 15: 126,429,179–126,429,288, 110 basesExon 14: 126,431,419–126,431,526, 108 basesExon 13: 126,435,268–126,435,303, 36 basesExon 12: 126,436,811–126,437,009, 199 basesExon 11: 126,440,449–126,440,549, 101 basesExon 10: 126,444,979–126,445,105, 127 basesExon 9: 126,446,759–126,446,886, 128 basesExon 8: 126,449,009–126,449,157, 149 basesExon 7: 126,456,349–126,456,454, 106 basesExon 6: 126,463,157–126,463,307, 151 basesExon 5: 126,473,309–126,473,466, 158 basesExon 4: 126,521,315–126,521,464, 150 basesExon 3: 126,526,538–126,526,687, 150 basesExon 2: 126,562,835–126,562,912, 78 basesExon 1: 127,000,455–127,000,770, 316 bases171015′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.8 kb of the gene's 577.4 kb; 2,337 of those bases code for the protein.

How a genome test reads KIRREL3

1

position in KIRREL3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 577.4 kb of KIRREL3, introns included, not only the 3.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KIRREL3 gene: kirre like nephrin family adhesion molecule 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/kirrel3

Vancouver

Dante Labs. KIRREL3 gene: kirre like nephrin family adhesion molecule 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kirrel3

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