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Gene

KALRN

kalirin RhoGEF kinase

Summary

Cytogenetic location
3q21.1-q21.2
Coordinates
Chromosome 3: 124,033,369–124,726,325 (GRCh38)
Exons
60 exons across 693 kb
Protein
2,986 amino acids
Also known as
duo, Hs.8004, TRAD, DUET, Kalirin, ARHGEF24, KALNC2
Previous symbols
HAPIP
MANE Select transcript
ENST00000682506.1NM_001388419.1
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KALRN yet. The test sequences your whole genome, so your data includes it all the same.

How KALRN is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where KALRN sits. KALRN and 11 genes near it on chromosome 3, from 123,340,412 to 125,419,282.Chromosome 33q21.1-q21.2p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29123.5 Mb124 Mb124.5 Mb125 MbADCY5: 123,282,296–123,449,795, reverse strandADCY5HACD2: 123,490,820–123,585,193, reverse strandHACD2MYLK: 123,610,049–123,884,375, reverse strandMYLKCCDC14: 123,897,305–123,961,443, reverse strandCCDC14ROPN1: 123,968,521–123,992,178, reverse strandROPN1KALRN: 124,033,369–124,726,325, forward strandKALRNUMPS: 124,730,433–124,749,384, forward strandUMPSITGB5: 124,757,793–124,901,418, reverse strandITGB5MUC13: 124,905,440–124,953,819, reverse strandMUC13HEG1: 124,965,710–125,056,056, reverse strandHEG1SLC12A8: 125,082,636–125,213,229, reverse strandSLC12A8ZNF148: 125,225,669–125,375,842, reverse strandZNF148Diagram of KALRN: 60 exons on the forward strand of chromosome 3Exon 1: 124,033,369–124,033,813, 445 basesExon 2: 124,227,990–124,228,064, 75 basesExon 3: 124,234,829–124,234,943, 115 basesExon 4: 124,264,498–124,264,690, 193 basesExon 5: 124,268,743–124,269,255, 513 basesExon 6: 124,298,791–124,298,913, 123 basesExon 7: 124,325,980–124,326,171, 192 basesExon 8: 124,329,861–124,329,992, 132 basesExon 9: 124,334,265–124,334,495, 231 basesExon 10: 124,347,143–124,347,265, 123 basesExon 11: 124,384,845–124,385,036, 192 basesExon 12: 124,395,135–124,395,343, 209 basesExon 13: 124,398,697–124,398,871, 175 basesExon 14: 124,413,470–124,413,665, 196 basesExon 15: 124,422,812–124,422,978, 167 basesExon 16: 124,430,656–124,430,775, 120 basesExon 17: 124,434,307–124,434,525, 219 basesExon 18: 124,438,888–124,439,037, 150 basesExon 19: 124,441,945–124,442,059, 115 basesExon 20: 124,446,161–124,446,276, 116 basesExon 21: 124,446,763–124,446,885, 123 basesExon 22: 124,455,177–124,455,359, 183 basesExon 23: 124,456,610–124,456,728, 119 basesExon 24: 124,461,890–124,461,956, 67 basesExon 25: 124,462,524–124,462,633, 110 basesExon 26: 124,474,663–124,474,732, 70 basesExon 27: 124,477,245–124,477,334, 90 basesExon 28: 124,482,808–124,482,900, 93 basesExon 29: 124,488,204–124,488,315, 112 basesExon 30: 124,490,694–124,490,884, 191 basesExon 31: 124,491,323–124,491,424, 102 basesExon 32: 124,492,740–124,492,882, 143 basesExon 33: 124,496,311–124,496,413, 103 basesExon 34: 124,562,843–124,563,089, 247 basesExon 35: 124,632,420–124,632,703, 284 basesExon 36: 124,633,852–124,633,953, 102 basesExon 37: 124,637,208–124,637,303, 96 basesExon 38: 124,650,808–124,650,938, 131 basesExon 39: 124,655,601–124,655,667, 67 basesExon 40: 124,657,448–124,657,551, 104 basesExon 41: 124,657,734–124,657,803, 70 basesExon 42: 124,658,431–124,658,517, 87 basesExon 43: 124,659,365–124,659,457, 93 basesExon 44: 124,660,923–124,660,973, 51 basesExon 45: 124,661,851–124,661,928, 78 basesExon 46: 124,666,449–124,666,634, 186 basesExon 47: 124,667,012–124,667,183, 172 basesExon 48: 124,671,660–124,671,898, 239 basesExon 49: 124,674,364–124,674,614, 251 basesExon 50: 124,678,190–124,678,313, 124 basesExon 51: 124,679,458–124,679,517, 60 basesExon 52: 124,693,804–124,693,831, 28 basesExon 53: 124,694,332–124,694,503, 172 basesExon 54: 124,696,134–124,696,255, 122 basesExon 55: 124,697,593–124,697,724, 132 basesExon 56: 124,699,869–124,700,033, 165 basesExon 57: 124,702,038–124,702,116, 79 basesExon 58: 124,712,935–124,713,135, 201 basesExon 59: 124,717,247–124,717,385, 139 basesExon 60: 124,718,925–124,726,325, 7,401 bases11020304050605′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 16.2 kb of the gene's 693 kb; 8,961 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). KALRN gene: kalirin RhoGEF kinase. Retrieved 17 October 2026, from https://dantelabs.com/genes/kalrn

Vancouver

Dante Labs. KALRN gene: kalirin RhoGEF kinase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kalrn

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