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Gene

HSD17B12

hydroxysteroid 17-beta dehydrogenase 12

Summary

Cytogenetic location
11p11.2
Coordinates
Chromosome 11: 43,680,738–43,856,615 (GRCh38)
Exons
11 exons across 175.9 kb
Protein
312 amino acids
Also known as
KAR, SDR12C1
MANE Select transcript
ENST00000278353.10NM_016142.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HSD17B12 yet. The test sequences your whole genome, so your data includes it all the same.

How HSD17B12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where HSD17B12 sits. HSD17B12 and 8 genes near it on chromosome 11, from 43,268,677 to 44,268,676.Chromosome 1111p11.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2543.4 Mb43.6 Mb43.8 Mb44 Mb44.2 MbAPI5: 43,311,955–43,344,531, forward strandAPI5TTC17: 43,358,910–43,494,933, forward strandTTC17HSD17B12: 43,680,738–43,856,615, forward strandHSD17B12ALKBH3: 43,880,811–43,920,370, forward strandALKBH3C11orf96: 43,942,637–43,943,878, forward strandC11orf96ACCSL: 44,047,981–44,059,977, forward strandACCSLACCS: 44,065,916–44,086,590, forward strandACCSEXT2: 44,095,648–44,284,513, forward strandEXT2ALX4: 44,260,440–44,310,139, reverse strandALX4Diagram of HSD17B12: 11 exons on the forward strand of chromosome 11Exon 1: 43,680,738–43,680,987, 250 basesExon 2: 43,750,911–43,750,957, 47 basesExon 3: 43,754,046–43,754,121, 76 basesExon 4: 43,798,320–43,798,427, 108 basesExon 5: 43,815,437–43,815,501, 65 basesExon 6: 43,816,347–43,816,391, 45 basesExon 7: 43,830,976–43,831,010, 35 basesExon 8: 43,838,317–43,838,398, 82 basesExon 9: 43,839,999–43,840,064, 66 basesExon 10: 43,854,715–43,854,864, 150 basesExon 11: 43,855,144–43,856,615, 1,472 bases1115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 175.9 kb; 939 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HSD17B12 gene: hydroxysteroid 17-beta dehydrogenase 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/hsd17b12

Vancouver

Dante Labs. HSD17B12 gene: hydroxysteroid 17-beta dehydrogenase 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hsd17b12

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