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Gene

HERC3

HECT and RLD domain containing E3 ubiquitin protein ligase 3

Summary

Cytogenetic location
4q22.1
Coordinates
Chromosome 4: 88,592,480–88,708,539 (GRCh38)
Exons
26 exons across 116.1 kb
Protein
1,050 amino acids
Also known as
KIAA0032
MANE Select transcript
ENST00000402738.6NM_014606.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HERC3 yet. The test sequences your whole genome, so your data includes it all the same.

How HERC3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where HERC3 sits. HERC3 and 9 genes near it on chromosome 4, from 88,150,510 to 89,150,509.Chromosome 44q22.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.288.2 Mb88.4 Mb88.6 Mb88.8 Mb89 MbABCG2: 88,088,127–88,231,818, reverse strandABCG2PPM1K: 88,257,620–88,284,769, reverse strandPPM1KHERC6: 88,378,734–88,443,098, forward strandHERC6HERC5: 88,457,086–88,506,188, forward strandHERC5PYURF: 88,520,986–88,523,794, reverse strandPYURFPIGY: 88,520,986–88,523,776, reverse strandPIGYHERC3: 88,592,480–88,708,539, forward strandHERC3NAP1L5: 88,695,913–88,697,829, reverse strandNAP1L5FAM13A: 88,725,893–89,111,398, reverse strandFAM13ATIGD2: 89,111,522–89,114,901, forward strandTIGD2Diagram of HERC3: 26 exons on the forward strand of chromosome 4Exon 1: 88,592,480–88,592,574, 95 basesExon 2: 88,595,557–88,595,614, 58 basesExon 3: 88,605,795–88,606,049, 255 basesExon 4: 88,649,840–88,649,999, 160 basesExon 5: 88,652,012–88,652,088, 77 basesExon 6: 88,652,869–88,653,090, 222 basesExon 7: 88,654,042–88,654,133, 92 basesExon 8: 88,655,174–88,655,304, 131 basesExon 9: 88,655,875–88,656,035, 161 basesExon 10: 88,658,415–88,658,491, 77 basesExon 11: 88,662,431–88,662,555, 125 basesExon 12: 88,664,153–88,664,212, 60 basesExon 13: 88,667,377–88,667,488, 112 basesExon 14: 88,667,892–88,668,081, 190 basesExon 15: 88,669,860–88,670,023, 164 basesExon 16: 88,670,139–88,670,252, 114 basesExon 17: 88,676,218–88,676,241, 24 basesExon 18: 88,676,334–88,676,423, 90 basesExon 19: 88,677,964–88,678,134, 171 basesExon 20: 88,680,093–88,680,236, 144 basesExon 21: 88,681,159–88,681,325, 167 basesExon 22: 88,686,736–88,686,802, 67 basesExon 23: 88,687,217–88,687,299, 83 basesExon 24: 88,704,098–88,704,281, 184 basesExon 25: 88,704,508–88,704,610, 103 basesExon 26: 88,706,752–88,708,539, 1,788 bases1510152025265′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.9 kb of the gene's 116.1 kb; 3,153 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HERC3 gene: HECT and RLD domain containing E3 ubiquitin protein ligase 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/herc3

Vancouver

Dante Labs. HERC3 gene: HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/herc3

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