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Gene

GNAI1

G protein subunit alpha i1

Summary

Cytogenetic location
7q21.11
Coordinates
Chromosome 7: 80,134,831–80,226,181 (GRCh38)
Exons
8 exons across 91.4 kb
Protein
354 amino acids
MANE Select transcript
ENST00000649796.2NM_002069.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GNAI1 yet. The test sequences your whole genome, so your data includes it all the same.

How GNAI1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where GNAI1 sits. GNAI1 and 2 genes near it on chromosome 7, from 79,680,506 to 80,680,505.Chromosome 77q21.11p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.379.8 Mb80 Mb80.2 Mb80.4 Mb80.6 MbGNAI1: 80,134,831–80,226,181, forward strandGNAI1CD36: 80,369,532–80,679,277, forward strandCD36GNAT3: 80,458,635–80,512,064, reverse strandGNAT3Diagram of GNAI1: 8 exons on the forward strand of chromosome 7Exon 1: 1 known disease-causing siteExon 2: 3 known disease-causing sitesExon 5: 1 known disease-causing siteExon 6: 2 known disease-causing sitesExon 7: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 1: 80,134,831–80,135,278, 448 basesExon 2: 80,188,951–80,188,993, 43 basesExon 3: 80,189,090–80,189,231, 142 basesExon 4: 80,199,225–80,199,382, 158 basesExon 5: 80,203,704–80,203,832, 129 basesExon 6: 80,210,969–80,211,098, 130 basesExon 7: 80,212,716–80,212,869, 154 basesExon 8: 80,217,303–80,226,181, 8,879 bases124685′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 10.1 kb of the gene's 91.4 kb; 1,065 of those bases code for the protein.

How a genome test reads GNAI1

10

positions in GNAI1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 91.4 kb of GNAI1, introns included, not only the 10.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GNAI1 gene: G protein subunit alpha i1. Retrieved 17 October 2026, from https://dantelabs.com/genes/gnai1

Vancouver

Dante Labs. GNAI1 gene: G protein subunit alpha i1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gnai1

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