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Gene

FTO

FTO alpha-ketoglutarate dependent dioxygenase

Summary

Cytogenetic location
16q12.2
Coordinates
Chromosome 16: 53,704,156–54,121,941 (GRCh38)
Exons
9 exons across 417.8 kb
Protein
505 amino acids
Also known as
KIAA1752, MGC5149, ALKBH9, IFEX9
MANE Select transcript
ENST00000471389.6NM_001080432.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Trait report that reads FTO

How FTO is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where FTO sits. FTO and 5 genes near it on chromosome 16, from 53,286,370 to 54,539,727.Chromosome 1616q12.2p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.353.4 Mb53.6 Mb53.8 Mb54 Mb54.2 Mb54.4 MbCHD9: 53,054,968–53,329,150, forward strandCHD9RBL2: 53,433,977–53,491,668, forward strandRBL2AKTIP: 53,490,502–53,504,411, reverse strandAKTIPRPGRIP1L: 53,598,153–53,703,938, reverse strandRPGRIP1LFTO: 53,704,156–54,121,941, forward strandFTOIRX3: 54,283,281–54,287,469, reverse strandIRX3Diagram of FTO: 9 exons on the forward strand of chromosome 16Exon 1: 53,704,156–53,704,229, 74 basesExon 2: 53,810,140–53,810,217, 78 basesExon 3: 53,825,864–53,826,491, 628 basesExon 4: 53,844,155–53,844,298, 144 basesExon 5: 53,873,786–53,873,865, 80 basesExon 6: 53,879,844–53,879,987, 144 basesExon 7: 53,888,832–53,888,951, 120 basesExon 8: 53,933,985–53,934,109, 125 basesExon 9: 54,111,762–54,121,941, 10,180 bases1246895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 11.6 kb of the gene's 417.8 kb; 1,518 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). FTO gene: FTO alpha-ketoglutarate dependent dioxygenase. Retrieved 16 October 2026, from https://dantelabs.com/genes/fto

Vancouver

Dante Labs. FTO gene: FTO alpha-ketoglutarate dependent dioxygenase [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fto

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