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Gene

ESR2

estrogen receptor 2

Summary

Cytogenetic location
14q23.2-q23.3
Coordinates
Chromosome 14: 64,228,317–64,294,371 (GRCh38)
Exons
9 exons across 66.1 kb
Protein
530 amino acids
Also known as
NR3A2, Erb, ER-beta
MANE Select transcript
ENST00000341099.6NM_001437.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ESR2 yet. The test sequences your whole genome, so your data includes it all the same.

How ESR2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 14, with a bracket where ESR2 sits. ESR2 and 9 genes near it on chromosome 14, from 63,761,344 to 64,761,343.Chromosome 1414q23.2-q23.3p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3363.8 Mb64 Mb64.2 Mb64.4 Mb64.6 MbSYNE2: 63,761,899–64,228,142, forward strandSYNE2ESR2: 64,228,317–64,294,371, reverse strandESR2MTHFD1: 64,388,031–64,463,457, forward strandMTHFD1ZBTB25: 64,430,818–64,505,232, reverse strandZBTB25AKAP5: 64,465,275–64,474,503, forward strandAKAP5ZBTB1: 64,502,152–64,533,690, forward strandZBTB1HSPA2: 64,535,905–64,546,173, forward strandHSPA2PPP1R36: 64,549,890–64,590,096, forward strandPPP1R36PLEKHG3: 64,704,102–64,750,249, forward strandPLEKHG3SPTB: 64,746,283–64,880,019, reverse strandSPTBDiagram of ESR2: 9 exons on the reverse strand of chromosome 14Exon 9: 64,228,317–64,233,323, 5,007 basesExon 8: 64,234,970–64,235,150, 181 basesExon 7: 64,249,546–64,249,679, 134 basesExon 6: 64,257,226–64,257,364, 139 basesExon 5: 64,260,449–64,260,748, 300 basesExon 4: 64,268,795–64,268,911, 117 basesExon 3: 64,279,981–64,280,153, 173 basesExon 2: 64,282,624–64,283,075, 452 basesExon 1: 64,294,033–64,294,371, 339 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.8 kb of the gene's 66.1 kb; 1,593 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). ESR2 gene: estrogen receptor 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/esr2

Vancouver

Dante Labs. ESR2 gene: estrogen receptor 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/esr2

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