Gene
EFCAB3
EF-hand calcium binding domain 3
- HGNC 26379↗(opens in a new tab)
- Ensembl gene ENSG00000172421↗(opens in a new tab)
- NCBI Gene 146779↗(opens in a new tab)
Summary
- Cytogenetic location
- 17q23.2
- Coordinates
- Chromosome 17: 62,380,553–62,416,480 (GRCh38)
- Exons
- 10 exons across 35.9 kb
- Protein
- 438 amino acids
- Also known as
- FLJ25818
- MANE Select transcript
- ENST00000305286.8NM_173503.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
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No Genome Test report reads EFCAB3 yet. The test sequences your whole genome, so your data includes it all the same.
How EFCAB3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.5 kb of the gene's 35.9 kb; 1,317 of those bases code for the protein.
Sequencing EFCAB3
23Moderate
How hard EFCAB3 is to sequence with short reads, out of 100Each bar is the share of EFCAB3's exon bases in that kind of difficult region. The score weighs them by how much each costs a short-read call: 0 when no base is in any, 100 when every base is in all of them.
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 35%.32%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 30%.39%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 15%.0.2%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 10%.2.7%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 10%.0%
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). EFCAB3 gene: EF-hand calcium binding domain 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/efcab3
Dante Labs. EFCAB3 gene: EF-hand calcium binding domain 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/efcab3
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