Skip to content
Use your HSA or FSA funds

Traits

Traits linked to CHEK1

checkpoint kinase 1

The Human Phenotype Ontology links 7 traits to CHEK1, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the genitourinary system

TraitHow often it is seen
Abnormal meiosisAlways
Female infertilityAlways
Metaphase I oocyte maturation arrestOften (30–79%)
Abnormal sperm developmentNot recorded
Polycystic ovariesNot recorded

Abnormal cellular phenotype

TraitHow often it is seen
Abnormal oocyte morphologySometimes (5–29%)

Abnormality of prenatal development or birth

TraitHow often it is seen
Zygotic cleavage failureAlways

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to CHEK1 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test