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Gene

BEST4

bestrophin 4

Summary

Cytogenetic location
1p34.1
Coordinates
Chromosome 1: 44,783,585–44,788,170 (GRCh38)
Exons
9 exons across 4.6 kb
Protein
473 amino acids
Previous symbols
VMD2L2
MANE Select transcript
ENST00000372207.4NM_153274.3
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads BEST4 yet. The test sequences your whole genome, so your data includes it all the same.

How BEST4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 1, with a bracket where BEST4 sits. BEST4 and 14 genes near it on chromosome 1, from 44,285,878 to 45,285,877.Chromosome 11p34.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4444.4 Mb44.6 Mb44.8 Mb45 Mb45.2 MbERI3: 44,221,070–44,355,267, reverse strandERI3RNF220: 44,405,142–44,651,724, forward strandRNF220TMEM53: 44,635,237–44,674,619, reverse strandTMEM53ARMH1: 44,674,692–44,725,591, forward strandARMH1KIF2C: 44,739,810–44,767,767, forward strandKIF2CRPS8: 44,775,251–44,779,124, forward strandRPS8BEST4: 44,783,585–44,788,170, reverse strandBEST4PLK3: 44,799,915–44,805,995, forward strandPLK3DYNLT4: 44,805,885–44,807,417, reverse strandDYNLT4BTBD19: 44,808,506–44,817,381, forward strandPTCH2: 44,819,154–44,843,253, reverse strandPTCH2EIF2B3: 44,850,464–44,986,722, reverse strandEIF2B3HECTD3: 45,002,540–45,011,369, reverse strandHECTD3UROD: 45,010,950–45,015,577, forward strandURODZSWIM5: 45,016,395–45,306,209, reverse strandZSWIM5Diagram of BEST4: 9 exons on the reverse strand of chromosome 1Exon 9: 44,783,585–44,784,483, 899 basesExon 8: 44,784,629–44,784,783, 155 basesExon 7: 44,784,905–44,784,985, 81 basesExon 6: 44,785,108–44,785,305, 198 basesExon 5: 44,785,599–44,785,676, 78 basesExon 4: 44,786,074–44,786,228, 155 basesExon 3: 44,786,463–44,786,696, 234 basesExon 2: 44,787,372–44,787,466, 95 basesExon 1: 44,787,554–44,788,170, 617 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 4.6 kb; 1,422 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). BEST4 gene: bestrophin 4. Retrieved 16 October 2026, from https://dantelabs.com/genes/best4

Vancouver

Dante Labs. BEST4 gene: bestrophin 4 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/best4

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