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Gene

ARHGEF5

Rho guanine nucleotide exchange factor 5

Summary

Cytogenetic location
7q35
Coordinates
Chromosome 7: 144,355,402–144,380,632 (GRCh38)
Exons
15 exons across 25.2 kb
Protein
1,597 amino acids
Also known as
TIM, TIM1, GEF5, P60
MANE Select transcript
ENST00000056217.10NM_005435.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads ARHGEF5 yet. The test sequences your whole genome, so your data includes it all the same.

How ARHGEF5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where ARHGEF5 sits. ARHGEF5 and 17 genes near it on chromosome 7, from 143,868,017 to 144,868,016.Chromosome 77q35p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.3144 Mb144.2 Mb144.4 Mb144.6 Mb144.8 MbTCAF1: 143,850,360–143,903,890, reverse strandTCAF1OR2F2: 143,935,233–143,936,186, forward strandOR2F2OR2F1: 143,954,844–143,997,312, forward strandOR2F1OR6B1: 144,000,320–144,008,793, forward strandOR6B1OR2A5: 144,048,948–144,058,845, forward strandOR2A5OR2A25: 144,069,811–144,075,870, forward strandOR2A25OR2A12: 144,086,278–144,098,953, forward strandOR2A12OR2A2: 144,109,583–144,110,539, forward strandOR2A2OR2A14: 144,123,176–144,131,188, forward strandOR2A14ARHGEF35: 144,182,888–144,195,879, reverse strandARHGEF35CTAGE4: 144,183,466–144,186,080, forward strandCTAGE4OR2A42: 144,228,244–144,239,605, reverse strandOR2A42OR2A7: 144,254,975–144,264,792, reverse strandOR2A7CTAGE8: 144,266,674–144,269,288, reverse strandCTAGE8OR2A1: 144,312,419–144,322,737, forward strandOR2A1ARHGEF5: 144,355,402–144,380,632, forward strandARHGEF5NOBOX: 144,396,894–144,403,795, reverse strandNOBOXTPK1: 144,451,941–144,836,419, reverse strandTPK1Diagram of ARHGEF5: 15 exons on the forward strand of chromosome 7Exon 1: 144,355,402–144,355,501, 100 basesExon 2: 144,362,658–144,365,823, 3,166 basesExon 3: 144,366,355–144,366,412, 58 basesExon 4: 144,366,846–144,366,910, 65 basesExon 5: 144,367,102–144,367,355, 254 basesExon 6: 144,371,161–144,371,321, 161 basesExon 7: 144,371,877–144,372,029, 153 basesExon 8: 144,372,299–144,372,428, 130 basesExon 9: 144,372,683–144,372,757, 75 basesExon 10: 144,373,195–144,373,284, 90 basesExon 11: 144,374,732–144,374,889, 158 basesExon 12: 144,375,514–144,375,675, 162 basesExon 13: 144,377,120–144,377,190, 71 basesExon 14: 144,378,762–144,378,866, 105 basesExon 15: 144,379,899–144,380,632, 734 bases12468101214155′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.5 kb of the gene's 25.2 kb; 4,794 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). ARHGEF5 gene: Rho guanine nucleotide exchange factor 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/arhgef5

Vancouver

Dante Labs. ARHGEF5 gene: Rho guanine nucleotide exchange factor 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/arhgef5

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