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Gene

ARHGEF11

Rho guanine nucleotide exchange factor 11

Summary

Cytogenetic location
1q23.1
Coordinates
Chromosome 1: 156,934,840–157,045,742 (GRCh38)
Exons
41 exons across 110.9 kb
Protein
1,562 amino acids
Also known as
KIAA0380, GTRAP48, PDZ-RHOGEF
MANE Select transcript
ENST00000368194.8NM_198236.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ARHGEF11 yet. The test sequences your whole genome, so your data includes it all the same.

How ARHGEF11 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where ARHGEF11 sits. ARHGEF11 and 21 genes near it on chromosome 1, from 156,490,291 to 157,490,290.Chromosome 11q23.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44156.6 Mb156.8 Mb157 Mb157.2 Mb157.4 MbMEF2D: 156,463,727–156,501,266, reverse strandMEF2DIQGAP3: 156,525,405–156,572,604, reverse strandIQGAP3TTC24: 156,579,723–156,587,719, forward strandTTC24NAXE: 156,591,738–156,609,507, forward strandNAXEGPATCH4: 156,594,301–156,601,496, reverse strandGPATCH4HAPLN2: 156,619,331–156,626,590, forward strandHAPLN2BCAN: 156,641,390–156,659,532, forward strandBCANNES: 156,668,763–156,677,415, reverse strandNESCRABP2: 156,699,592–156,708,094, reverse strandISG20L2: 156,720,651–156,728,836, reverse strandMETTL25B: 156,728,442–156,736,960, forward strandMETTL25BMRPL24: 156,737,292–156,741,590, reverse strandMRPL24HDGF: 156,742,109–156,766,925, reverse strandHDGFPRCC: 156,750,610–156,800,818, forward strandPRCCSH2D2A: 156,806,235–156,817,014, reverse strandSH2D2ANTRK1: 156,815,636–156,881,850, forward strandNTRK1INSRR: 156,840,063–156,859,122, reverse strandINSRRPEAR1: 156,893,656–156,916,432, forward strandPEAR1LRRC71: 156,920,631–156,934,915, forward strandLRRC71ARHGEF11: 156,934,840–157,045,742, reverse strandARHGEF11ETV3L: 157,092,043–157,117,877, reverse strandETV3LETV3: 157,121,191–157,138,952, reverse strandETV3Diagram of ARHGEF11: 41 exons on the reverse strand of chromosome 1Exon 41: 156,934,840–156,936,058, 1,219 basesExon 40: 156,936,816–156,937,005, 190 basesExon 39: 156,937,249–156,937,496, 248 basesExon 38: 156,938,418–156,938,513, 96 basesExon 37: 156,939,548–156,939,910, 363 basesExon 36: 156,940,207–156,940,425, 219 basesExon 35: 156,941,372–156,941,433, 62 basesExon 34: 156,941,864–156,941,989, 126 basesExon 33: 156,942,690–156,942,780, 91 basesExon 32: 156,943,935–156,944,102, 168 basesExon 31: 156,944,358–156,944,433, 76 basesExon 30: 156,945,019–156,945,197, 179 basesExon 29: 156,946,045–156,946,162, 118 basesExon 28: 156,946,662–156,946,787, 126 basesExon 27: 156,946,936–156,947,015, 80 basesExon 26: 156,947,304–156,947,450, 147 basesExon 25: 156,947,769–156,947,956, 188 basesExon 24: 156,948,181–156,948,228, 48 basesExon 23: 156,948,319–156,948,498, 180 basesExon 22: 156,951,573–156,951,699, 127 basesExon 21: 156,954,892–156,954,921, 30 basesExon 20: 156,955,703–156,955,799, 97 basesExon 19: 156,956,420–156,956,564, 145 basesExon 18: 156,957,792–156,957,815, 24 basesExon 17: 156,958,742–156,958,864, 123 basesExon 16: 156,959,046–156,959,142, 97 basesExon 15: 156,960,418–156,960,460, 43 basesExon 14: 156,961,677–156,961,775, 99 basesExon 13: 156,963,203–156,963,304, 102 basesExon 12: 156,963,520–156,963,594, 75 basesExon 11: 156,967,987–156,968,124, 138 basesExon 10: 156,969,282–156,969,358, 77 basesExon 9: 156,969,998–156,970,043, 46 basesExon 8: 156,971,697–156,971,816, 120 basesExon 7: 156,976,983–156,977,054, 72 basesExon 6: 156,978,204–156,978,382, 179 basesExon 5: 156,979,229–156,979,286, 58 basesExon 4: 156,980,437–156,980,486, 50 basesExon 3: 156,984,339–156,984,437, 99 basesExon 2: 156,986,082–156,986,173, 92 basesExon 1: 157,044,299–157,045,742, 1,444 bases412515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.3 kb of the gene's 110.9 kb; 4,689 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). ARHGEF11 gene: Rho guanine nucleotide exchange factor 11. Retrieved 16 October 2026, from https://dantelabs.com/genes/arhgef11

Vancouver

Dante Labs. ARHGEF11 gene: Rho guanine nucleotide exchange factor 11 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/arhgef11

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