Risk score · Metabolism & body
Type 1 Diabetes Polygenic Risk Score
Type 1 diabetes is an autoimmune condition in which the body destroys its own insulin-making cells. It usually starts in childhood or early adulthood.
A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.
A polygenic score for Type 1 diabetes (T1D)
Genetic variants
- 33
Method
- SNP associations curated from the literature
Built from studies of
- European 100%
Developed in
- European 100%
Evaluated in
- European 67%, African 17%, Multi-ancestry 17%
Published
Oram RA et al. (2015). A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults. Diabetes Care.
References
- Noble JA, Valdes AM, Varney MD, Carlson JA, Moonsamy P, Fear AL, 2010. HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. Diabetes
Other metabolism & body risk scores
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