Risk score · Mental health & wellbeing
Depression Polygenic Score
Depression is common and treatable. Life events and circumstances matter most, and genetics adds a modest part of the risk.
A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.
Included with every kit
How the score works
A polygenic score for Major depression
Genetic variants
- 1,138
Method
- PRSice
Built from studies of
- European 100%
Evaluated in
- European 100%
Published
Coleman JRI et al. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Mol Psychiatry.
References
- Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, 2018. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nat Genet
Other mental health & wellbeing risk scores
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One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. Physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances.
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