Trait

Vocal tremor

A wavering, unsteady voice that reflects involuntary and approximately sinusoidal oscillation of motor unit firings of laryngeal muscles. Vocal tremor results in low frequency modulations of voice frequency or amplitude and intermittent voice instability.

HPO HP:0012477

Also called: Shakey voice
Body system: Abnormality of the nervous system

This page as data

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2 genes linked to Vocal tremor

Changes in these genes cause rare conditions in which Vocal tremor is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ANO3anoctamin 3	Often (30–79%)	In 1 condition
NOTCH2NLCnotch 2 N-terminal like C	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Action tremor

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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