Trait

Retinal arteriolar macroaneurysms

Acquired focal dilatations of branches of the retinal artery, usually second-order retinal arterioles, that range in size from 100 to 200 micrometers in diameter. Macroaneurysms are generally located at the temporal retina and may be hemorrhagic or exudative.

HPO HP:0025355

Body system: Abnormality of head or neck Abnormality of the cardiovascular system Abnormality of the eye

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1 gene linked to Retinal arteriolar macroaneurysms

Changes in these genes cause rare conditions in which Retinal arteriolar macroaneurysms is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
IGFBP7insulin like growth factor binding protein 7	Always	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of retinal arteries

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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