Trait
Lamellar cataract
A congenital cataract in which opacity is limited to layers of the lens external to the nucleus (i.e., the perinuclear region), i.e., between the nuclear and cortical layers of the lens.
Summary
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test7 genes linked to Lamellar cataract
Changes in these genes cause rare conditions in which Lamellar cataract is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CRYGScrystallin gamma S | Always | In 1 condition |
| MIPmajor intrinsic protein of lens fiber | Very often (80–99%) | In 1 condition |
| CRYGBcrystallin gamma B | Often (30–79%) | In 1 condition |
| LIM2lens intrinsic membrane protein 2 | Often (30–79%) | In 1 condition |
| BFSP1beaded filament structural protein 1 | Not recorded | In 1 condition |
| CRYBA4crystallin beta A4 | Not recorded | In 1 condition |
| HSF4heat shock transcription factor 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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