Trait
Hearing loss, high-frequency
Clinical name: High-frequency hearing impairment
A type of hearing impairment affecting primarily the higher frequencies of sound (3,000 to 6,000 Hz).
Summary
- Also called
- High frequency hearing loss, Progressive high frequency hearing loss, High-frequency deafness, Progressive high-frequency hearing loss
- Body system
- Abnormality of the ear
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Hearing loss, high-frequency, and the rest of your genome, with one test.
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Get my Genome Test8 genes linked to Hearing loss, high-frequency
Changes in these genes cause rare conditions in which Hearing loss, high-frequency is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| POLRMTRNA polymerase mitochondrial | Sometimes (5–29%) | In 1 condition |
| AP1S2adaptor related protein complex 1 subunit sigma 2 | Not recorded | In 1 condition |
| DSPPdentin sialophosphoprotein | Not recorded | In 1 condition |
| GJB3gap junction protein beta 3 | Not recorded | In 1 condition |
| LMX1ALIM homeobox transcription factor 1 alpha | Not recorded | In 1 condition |
| MYH9myosin heavy chain 9 | Not recorded | In 1 condition |
| RPGRretinitis pigmentosa GTPase regulator | Not recorded | In 1 condition |
| SMPXsmall muscle protein X-linked | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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