Trait

Darkening of the forehead

Clinical name: Forehead hyperpigmentation

Body system: Abnormality of head or neck Abnormality of the integument

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/forehead-hyperpigmentation.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

Read the genes linked to Darkening of the forehead, and the rest of your genome, with one test.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test

1 gene linked to Darkening of the forehead

Changes in these genes cause rare conditions in which Darkening of the forehead is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
SEC23ASEC23 homolog A, COPII component	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of the forehead Irregular hyperpigmentation

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.