Trait

Elevated coagulation factor V activity

Increased activity of coagulation factor V, Factor V, which is activated to factor Va by means of minute amounts of thrombin (and inactivated by larger amounts of thrombin). Activated factor V (fVa) is a cofactor in the formation of the prothrombinase complex.

HPO HP:0011996

Also called: Elevated factor V activity, Plasma factor V elevated
Body system: Abnormality of blood and blood-forming tissues

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1 gene linked to Elevated coagulation factor V activity

Changes in these genes cause rare conditions in which Elevated coagulation factor V activity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
AHCYadenosylhomocysteinase	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal coagulation factor V activity

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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