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Trait

Decreased circulating IgG3 concentration

A reduction in immunoglobulin levels of the IgG3 subclass in the blood circulation.

HPO HP:0032137

Summary

Also called
Decreased circulating IgG3 level, Decreased IgG3 level in blood
Body system
Abnormal cellular phenotypeAbnormality of blood and blood-forming tissuesLaboratory abnormalityAbnormality of the immune system

1 gene linked to Decreased circulating IgG3 concentration

Changes in these genes cause rare conditions in which Decreased circulating IgG3 concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
IFIH1interferon induced with helicase C domain 1AlwaysIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Decreased circulating IgG subclass concentration

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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