Trait

Bladder hernia

Clinical name: Cystocele

Anterior vaginal wall prolapse with bulging of the bladder into the vagina.

HPO HP:0100645

Also called: Dropped bladder, Bladder prolapse, Prolapsed bladder
Body system: Abnormality of the genitourinary system

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2 genes linked to Bladder hernia

Changes in these genes cause rare conditions in which Bladder hernia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
SMAD3SMAD family member 3	Sometimes (5–29%)	In 1 condition
COL3A1collagen type III alpha 1 chain	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal bladder morphology Pelvic organ prolapse

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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