Trait

C3 nephritic factor positivity

The presence of autoantibodies (immunoglobulins) in the serum that react against C3 convertase (C3bBb).

Body system: Abnormality of the immune system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/c3-nephritic-factor-positivity.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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1 gene linked to C3 nephritic factor positivity

Changes in these genes cause rare conditions in which C3 nephritic factor positivity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
DGKEdiacylglycerol kinase epsilon	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Autoimmune antibody positivity

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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