Trait

Anterior lenticonus

A conical projection of the anterior surface of the lens, occurring as a developmental anomaly.

HPO HP:0011501

Body system: Abnormality of the eye

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4 genes linked to Anterior lenticonus

Changes in these genes cause rare conditions in which Anterior lenticonus is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
COL4A5collagen type IV alpha 5 chain	Often (30–79%)	In 3 conditions
COL4A3collagen type IV alpha 3 chain	Sometimes (5–29%)	In 2 conditions
COL4A4collagen type IV alpha 4 chain	Sometimes (5–29%)	In 3 conditions
COL4A6collagen type IV alpha 6 chain	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Lenticonus

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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