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Trait

Loss of fat tissue

Clinical name: Adipose tissue loss

A reduction in the amount of adipose tissue (fat) compared with the amount previously present in an individual.

HPO HP:0008887

Summary

Body system
Abnormality of the musculoskeletal system

4 genes linked to Loss of fat tissue

Changes in these genes cause rare conditions in which Loss of fat tissue is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
BLMBLM RecQ like helicaseVery often (80–99%)In 1 condition
INSRinsulin receptorNot recordedIn 1 condition
LMNAlamin A/CNot recordedIn 1 condition
PSMB8proteasome 20S subunit beta 8Not recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Decreased fat tissue

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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