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Trait

Acephalic spermatozoa

Spermatozoa with very small cranial ends devoid of any nuclear material, that is, lacking a typical sperm head.

HPO HP:0012869

Summary

Body system
Abnormality of the genitourinary system

7 genes linked to Acephalic spermatozoa

Changes in these genes cause rare conditions in which Acephalic spermatozoa is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
ACTL7Aactin like 7AAlwaysIn 1 condition
BRDTbromodomain testis associatedAlwaysIn 1 condition
CEP112centrosomal protein 112AlwaysIn 1 condition
PMFBP1polyamine modulated factor 1 binding protein 1AlwaysIn 2 conditions
SPACA1sperm acrosome associated 1AlwaysIn 1 condition
SUN5Sad1 and UNC84 domain containing 5AlwaysIn 2 conditions
TSGA10testis specific 10AlwaysIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal sperm head morphology

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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