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Trait

Abnormal regulatory T cell proportion

Abnormal increase or decrease of the regulatory (Treg) CD4+ T cell subpopulation, commonly characterized by the CD127lowCD25hi phenotype, with the optional additional positivity for FoxP3, measured as percentage of total CD4+ T cells in the blood, compared to a reference range for a given sex and age-group.

HPO HP:0020111

Summary

Also called
Abnormal CD4+CD25+ regulatory T cell proportion, Abnormal CD4+CD25+ Treg cell proportion, Abnormal proportion of regulatory T cells, Abnormal Treg proportion
Body system
Abnormality of blood and blood-forming tissuesAbnormality of the immune system

0 genes linked to Abnormal regulatory T cell proportion

The Human Phenotype Ontology links no gene to Abnormal regulatory T cell proportion itself. The narrower traits below list theirs.

Narrower traits

Broader traits

Abnormal CD4+ T cell subset proportion

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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