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Trait

Abnormal class-switched memory B cell proportion

A deviation of the normal proportion of class-switched memory B cells (CD19+/CD27+/IgM-/IgD-) in circulation relative to the total number of B cells. Marginal zone B cells undergo limited somatic hypermutation and produce high-affinity IgM and some IgG, whereas class-switched memory B cells synthetize IgG, IgM, and IgA.

HPO HP:0030386

Summary

Also called
Abnormal proportion of CD19+CD27+IgD- cells, Abnormal proportion of class-switched memory B cells
Body system
Abnormality of blood and blood-forming tissuesAbnormality of the immune system

0 genes linked to Abnormal class-switched memory B cell proportion

The Human Phenotype Ontology links no gene to Abnormal class-switched memory B cell proportion itself. The narrower traits below list theirs.

Narrower traits

Broader traits

Abnormal memory B cell proportion

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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