Gene
ZC3HAV1
zinc finger CCCH-type containing, antiviral 1
- HGNC 23721↗(opens in a new tab)
- Ensembl gene ENSG00000105939↗(opens in a new tab)
- NCBI Gene 56829↗(opens in a new tab)
Summary
- Cytogenetic location
- 7q34
- Coordinates
- Chromosome 7: 139,043,515–139,109,720 (GRCh38)
- Exons
- 13 exons across 66.2 kb
- Protein
- 902 amino acids
- Also known as
- ZAP, FLB6421, FLJ13288, MGC48898, ZC3HDC2, ZC3H2, PARP13, ARTD13
- MANE Select transcript
- ENST00000242351.10NM_020119.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
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How ZC3HAV1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 7.2 kb of the gene's 66.2 kb; 2,709 of those bases code for the protein.
Sequencing ZC3HAV1
2Easy
How hard ZC3HAV1 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Almost all of ZC3HAV1's exons sit where short reads map cleanly.
What adds to it: the share of ZC3HAV1's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. On its own, a gene wholly in this kind of region would score 100.0.1%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. On its own, a gene wholly in this kind of region would score 60.0%
- Shared with chrYThe pseudoautosomal regions and the X-transposed region, where chrX and chrY carry the same or nearly the same sequence, so a read from one may be placed on the other. On its own, a gene wholly in this kind of region would score 60.0%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. On its own, a gene wholly in this kind of region would score 50.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. On its own, a gene wholly in this kind of region would score 30.3.1%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. On its own, a gene wholly in this kind of region would score 20.5.7%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of ZC3HAV1's exon bases in that kind of difficult region. Any one kind can make a gene hard on its own, and each further kind adds less: 0 when no base is in any, 100 when every base is where reads cannot be placed uniquely.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). ZC3HAV1 gene: zinc finger CCCH-type containing, antiviral 1. Retrieved 19 October 2026, from https://dantelabs.com/genes/zc3hav1
Dante Labs. ZC3HAV1 gene: zinc finger CCCH-type containing, antiviral 1 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/zc3hav1
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