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Gene

UPF2

UPF2 regulator of nonsense mediated mRNA decay

Summary

Cytogenetic location
10p14
Coordinates
Chromosome 10: 11,920,022–12,042,809 (GRCh38)
Exons
22 exons across 122.8 kb
Protein
1,272 amino acids
Also known as
RENT2, DKFZP434D222, KIAA1408, smg-3
MANE Select transcript
ENST00000357604.10NM_015542.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads UPF2 yet. The test sequences your whole genome, so your data includes it all the same.

How UPF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 10, with a bracket where UPF2 sits. UPF2 and 8 genes near it on chromosome 10, from 11,481,416 to 12,481,415.Chromosome 1010p14p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.311.6 Mb11.8 Mb12 Mb12.2 Mb12.4 MbUSP6NL: 11,460,328–11,611,807, reverse strandUSP6NLECHDC3: 11,742,357–11,767,362, forward strandECHDC3PROSER2: 11,823,339–11,872,277, forward strandPROSER2UPF2: 11,920,022–12,042,809, reverse strandUPF2DHTKD1: 12,068,926–12,125,946, forward strandDHTKD1SEC61A2: 12,129,637–12,169,961, forward strandSEC61A2NUDT5: 12,164,844–12,196,155, reverse strandNUDT5CDC123: 12,195,910–12,250,595, forward strandCDC123CAMK1D: 12,349,513–12,835,545, forward strandCAMK1DDiagram of UPF2: 22 exons on the reverse strand of chromosome 10Exon 22: 11,920,022–11,921,307, 1,286 basesExon 21: 11,929,865–11,929,985, 121 basesExon 20: 11,931,641–11,931,782, 142 basesExon 19: 11,936,545–11,936,712, 168 basesExon 18: 11,942,665–11,942,763, 99 basesExon 17: 11,943,064–11,943,168, 105 basesExon 16: 11,948,369–11,948,508, 140 basesExon 15: 11,952,066–11,952,249, 184 basesExon 14: 11,955,232–11,955,507, 276 basesExon 13: 11,956,320–11,956,523, 204 basesExon 12: 11,959,171–11,959,356, 186 basesExon 11: 11,964,009–11,964,125, 117 basesExon 10: 11,967,341–11,967,454, 114 basesExon 9: 11,979,057–11,979,165, 109 basesExon 8: 11,997,672–11,997,757, 86 basesExon 7: 11,999,906–12,000,009, 104 basesExon 6: 12,001,676–12,001,825, 150 basesExon 5: 12,004,530–12,004,727, 198 basesExon 4: 12,014,024–12,014,184, 161 basesExon 3: 12,028,745–12,029,524, 780 basesExon 2: 12,035,059–12,035,441, 383 basesExon 1: 12,042,755–12,042,809, 55 bases22201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.2 kb of the gene's 122.8 kb; 3,819 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). UPF2 gene: UPF2 regulator of nonsense mediated mRNA decay. Retrieved 17 October 2026, from https://dantelabs.com/genes/upf2

Vancouver

Dante Labs. UPF2 gene: UPF2 regulator of nonsense mediated mRNA decay [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/upf2

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