Gene
UHRF2
ubiquitin like with PHD and ring finger domains 2
- HGNC 12557↗(opens in a new tab)
- Ensembl gene ENSG00000147854↗(opens in a new tab)
- NCBI Gene 115426↗(opens in a new tab)
Summary
- Cytogenetic location
- 9p24.1
- Coordinates
- Chromosome 9: 6,413,199–6,507,054 (GRCh38)
- Exons
- 16 exons across 93.9 kb
- Protein
- 802 amino acids
- Also known as
- RNF107, NIRF, URF2, MGC33463, TDRD23
- MANE Select transcript
- ENST00000276893.10NM_152896.3
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
This page as data
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How UHRF2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.6 kb of the gene's 93.9 kb; 2,409 of those bases code for the protein.
Sequencing UHRF2
12Moderate
How hard UHRF2 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Some of UHRF2's exons sit where short reads can miss or misplace a change.
What adds to it: the share of UHRF2's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 35%.4.5%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 30%.29%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 15%.2.2%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 10%.10%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 10%.0%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of UHRF2's exon bases in that kind of difficult region. Any one kind can make a gene hard on its own, and each further kind adds less: 0 when no base is in any, 100 when every base is where reads cannot be placed uniquely.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). UHRF2 gene: ubiquitin like with PHD and ring finger domains 2. Retrieved 18 October 2026, from https://dantelabs.com/genes/uhrf2
Dante Labs. UHRF2 gene: ubiquitin like with PHD and ring finger domains 2 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/uhrf2
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