Gene
TRIB2
tribbles pseudokinase 2
- HGNC 30809↗(opens in a new tab)
- Ensembl gene ENSG00000071575↗(opens in a new tab)
- NCBI Gene 28951↗(opens in a new tab)
Summary
- Cytogenetic location
- 2p24.3
- Coordinates
- Chromosome 2: 12,716,936–12,742,734 (GRCh38)
- Exons
- 3 exons across 25.8 kb
- Protein
- 343 amino acids
- Also known as
- TRB2, GS3955
- MANE Select transcript
- ENST00000155926.9NM_021643.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
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No Genome Test report reads TRIB2 yet. The test sequences your whole genome, so your data includes it all the same.
How TRIB2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.3 kb of the gene's 25.8 kb; 1,032 of those bases code for the protein.
Sequencing TRIB2
4Easy
How hard TRIB2 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Almost all of TRIB2's exons sit where short reads map cleanly.
What adds to it: the share of TRIB2's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. On its own, a gene wholly in this kind of region would score 100.0%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. On its own, a gene wholly in this kind of region would score 60.0%
- Shared with chrYThe pseudoautosomal regions and the X-transposed region, where chrX and chrY carry the same or nearly the same sequence, so a read from one may be placed on the other. On its own, a gene wholly in this kind of region would score 60.0%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. On its own, a gene wholly in this kind of region would score 50.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. On its own, a gene wholly in this kind of region would score 30.7.1%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. On its own, a gene wholly in this kind of region would score 20.11%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of TRIB2's exon bases in that kind of difficult region. Any one kind can make a gene hard on its own, and each further kind adds less: 0 when no base is in any, 100 when every base is where reads cannot be placed uniquely.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). TRIB2 gene: tribbles pseudokinase 2. Retrieved 20 October 2026, from https://dantelabs.com/genes/trib2
Dante Labs. TRIB2 gene: tribbles pseudokinase 2 [Internet]. [cited 20 October 2026]. Available from: https://dantelabs.com/genes/trib2
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