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Gene

TRHDE

thyrotropin releasing hormone degrading enzyme

Summary

Cytogenetic location
12q21.1
Coordinates
Chromosome 12: 72,272,370–72,670,758 (GRCh38)
Exons
19 exons across 398.4 kb
Protein
1,069 amino acids
Also known as
PGPEP2, TRH-DE, PAP-II
MANE Select transcript
ENST00000261180.10NM_013381.3
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TRHDE yet. The test sequences your whole genome, so your data includes it all the same.

How TRHDE is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where TRHDE sits. TRHDE and 2 genes near it on chromosome 12, from 71,873,981 to 73,069,147.Chromosome 1212q21.1p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3372 Mb72.2 Mb72.4 Mb72.6 Mb72.8 Mb73 MbTBC1D15: 71,839,707–71,927,248, forward strandTBC1D15TPH2: 71,938,845–72,186,618, forward strandTPH2TRHDE: 72,272,370–72,670,758, forward strandTRHDEDiagram of TRHDE: 19 exons on the forward strand of chromosome 12Exon 1: 72,272,370–72,273,557, 1,188 basesExon 2: 72,286,681–72,286,954, 274 basesExon 3: 72,377,995–72,378,121, 127 basesExon 4: 72,469,758–72,469,912, 155 basesExon 5: 72,473,067–72,473,180, 114 basesExon 6: 72,499,498–72,499,635, 138 basesExon 7: 72,542,291–72,542,356, 66 basesExon 8: 72,562,165–72,562,230, 66 basesExon 9: 72,562,853–72,563,040, 188 basesExon 10: 72,568,568–72,568,656, 89 basesExon 11: 72,575,255–72,575,388, 134 basesExon 12: 72,575,487–72,575,542, 56 basesExon 13: 72,618,891–72,619,038, 148 basesExon 14: 72,621,108–72,621,205, 98 basesExon 15: 72,621,644–72,621,751, 108 basesExon 16: 72,652,322–72,652,489, 168 basesExon 17: 72,653,016–72,653,156, 141 basesExon 18: 72,656,927–72,657,008, 82 basesExon 19: 72,663,052–72,670,758, 7,707 bases151015195′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 11 kb of the gene's 398.4 kb; 3,210 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TRHDE gene: thyrotropin releasing hormone degrading enzyme. Retrieved 17 October 2026, from https://dantelabs.com/genes/trhde

Vancouver

Dante Labs. TRHDE gene: thyrotropin releasing hormone degrading enzyme [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/trhde

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