Gene
TRB
T cell receptor beta locus
Summary
- Cytogenetic location
- 7q34
- Previous symbols
- TCRB, TRB@
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
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Sequencing TRB
1
position in TRB where ClinVar classes a change as pathogenic or likely pathogenic
1 of them (100%) falls in a region short reads find hard.
- Segmental duplicationsCopies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy. (1 site)
ClinVar pathogenic variants (1)
The TRB variants ClinVar classifies pathogenic or likely pathogenic for any condition, reviewed by at least one submitter with criteria, and the most reviewed of them. It is ClinVar's public record of the gene, never a result.
- Pathogenic 1
| Variant | Conditions | ClinVar classification | Review status |
|---|---|---|---|
| NC_000007.14:g.142749126_142753040dup (opens in a new tab) | hereditary chronic pancreatitis | Pathogenic | ★★★★1 star out of 4 criteria provided, single submitter |
External links
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- Data release 2026.10.19-9814e911.
Cite this page
Dante Labs. (n.d.). TRB gene: T cell receptor beta locus. Retrieved 21 October 2026, from https://dantelabs.com/genes/trb
Dante Labs. TRB gene: T cell receptor beta locus [Internet]. [cited 21 October 2026]. Available from: https://dantelabs.com/genes/trb
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