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Gene

TPH1

tryptophan hydroxylase 1

Summary

Cytogenetic location
11p15.1
Coordinates
Chromosome 11: 18,017,555–18,046,269 (GRCh38)
Exons
11 exons across 28.7 kb
Protein
444 amino acids
Previous symbols
TPRH, TPH
MANE Select transcript
ENST00000682019.1NM_004179.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TPH1 yet. The test sequences your whole genome, so your data includes it all the same.

How TPH1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where TPH1 sits. TPH1 and 19 genes near it on chromosome 11, from 17,531,912 to 18,531,911.Chromosome 1111p15.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2517.6 Mb17.8 Mb18 Mb18.2 Mb18.4 MbUSH1C: 17,493,895–17,544,435, reverse strandUSH1COTOG: 17,547,259–17,647,150, forward strandOTOGMYOD1: 17,719,565–17,722,136, forward strandMYOD1KCNC1: 17,734,724–17,856,811, forward strandKCNC1SERGEF: 17,788,043–18,013,199, reverse strandSERGEFTPH1: 18,017,555–18,046,269, reverse strandTPH1SAAL1: 18,069,935–18,106,108, reverse strandSAAL1MRGPRX3: 18,120,955–18,138,488, forward strandMRGPRX3MRGPRX4: 18,172,837–18,174,280, forward strandMRGPRX4SAA4: 18,229,731–18,236,860, reverse strandSAA4SAA2-SAA4: 18,231,423–18,248,635, reverse strandSAA2-SAA4SAA2: 18,238,236–18,248,668, reverse strandSAA2SAA1: 18,266,118–18,271,130, forward strandSAA1HPS5: 18,278,668–18,322,523, reverse strandHPS5GTF2H1: 18,322,254–18,367,881, forward strandGTF2H1LDHA: 18,394,347–18,408,425, forward strandLDHALDHC: 18,412,286–18,452,069, forward strandLDHCLDHAL6A: 18,455,823–18,479,601, forward strandLDHAL6ATSG101: 18,468,336–18,526,965, reverse strandTSG101UEVLD: 18,529,607–18,588,747, reverse strandUEVLDDiagram of TPH1: 11 exons on the reverse strand of chromosome 11Exon 11: 18,017,555–18,021,165, 3,611 basesExon 10: 18,022,798–18,022,931, 134 basesExon 9: 18,023,888–18,023,983, 96 basesExon 8: 18,025,575–18,025,701, 127 basesExon 7: 18,026,490–18,026,625, 136 basesExon 6: 18,029,165–18,029,361, 197 basesExon 5: 18,029,512–18,029,579, 68 basesExon 4: 18,033,274–18,033,374, 101 basesExon 3: 18,035,959–18,036,142, 184 basesExon 2: 18,040,646–18,040,788, 143 basesExon 1: 18,046,241–18,046,269, 29 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.8 kb of the gene's 28.7 kb; 1,335 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TPH1 gene: tryptophan hydroxylase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/tph1

Vancouver

Dante Labs. TPH1 gene: tryptophan hydroxylase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tph1

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