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Gene

TMPRSS11B

transmembrane serine protease 11B

Summary

Cytogenetic location
4q13.2
Coordinates
Chromosome 4: 68,226,653–68,245,694 (GRCh38)
Exons
10 exons across 19 kb
Protein
416 amino acids
Also known as
HATL5
MANE Select transcript
ENST00000332644.6NM_182502.3
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TMPRSS11B yet. The test sequences your whole genome, so your data includes it all the same.

How TMPRSS11B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where TMPRSS11B sits. TMPRSS11B and 8 genes near it on chromosome 4, from 67,736,174 to 68,736,173.Chromosome 44q13.2p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.267.8 Mb68 Mb68.2 Mb68.4 Mb68.6 MbGNRHR: 67,737,118–67,754,403, reverse strandGNRHRTMPRSS11D: 67,820,876–67,884,002, reverse strandTMPRSS11DTMPRSS11A: 67,909,395–67,964,140, reverse strandTMPRSS11ATMPRSS11F: 68,053,198–68,129,869, reverse strandTMPRSS11FTMPRSS11B: 68,226,653–68,245,694, reverse strandTMPRSS11BYTHDC1: 68,310,387–68,350,110, reverse strandYTHDC1TMPRSS11E: 68,447,428–68,500,544, forward strandTMPRSS11EUGT2B17: 68,516,301–68,627,039, reverse strandUGT2B17UGT2B15: 68,646,590–68,670,684, reverse strandUGT2B15Diagram of TMPRSS11B: 10 exons on the reverse strand of chromosome 4Exon 10: 68,226,653–68,228,072, 1,420 basesExon 9: 68,228,742–68,228,884, 143 basesExon 8: 68,229,257–68,229,516, 260 basesExon 7: 68,231,203–68,231,380, 178 basesExon 6: 68,232,378–68,232,416, 39 basesExon 5: 68,234,463–68,234,623, 161 basesExon 4: 68,236,002–68,236,069, 68 basesExon 3: 68,236,151–68,236,266, 116 basesExon 2: 68,241,689–68,241,804, 116 basesExon 1: 68,245,551–68,245,694, 144 bases10864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 19 kb; 1,251 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TMPRSS11B gene: transmembrane serine protease 11B. Retrieved 17 October 2026, from https://dantelabs.com/genes/tmprss11b

Vancouver

Dante Labs. TMPRSS11B gene: transmembrane serine protease 11B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tmprss11b

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