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Gene

TMEM161B

transmembrane protein 161B

Summary

Cytogenetic location
5q14.3
Coordinates
Chromosome 5: 88,195,047–88,268,845 (GRCh38)
Exons
12 exons across 73.8 kb
Protein
487 amino acids
Also known as
MGC33214
MANE Select transcript
ENST00000296595.11NM_153354.5
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TMEM161B yet. The test sequences your whole genome, so your data includes it all the same.

How TMEM161B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 5, with a bracket where TMEM161B sits. TMEM161B and 1 gene near it on chromosome 5, from 87,731,946 to 88,731,945.Chromosome 55q14.3p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.387.8 Mb88 Mb88.2 Mb88.4 Mb88.6 MbTMEM161B: 88,195,047–88,268,845, reverse strandTMEM161BMEF2C: 88,717,117–88,904,257, reverse strandMEF2CDiagram of TMEM161B: 12 exons on the reverse strand of chromosome 5Exon 12: 88,195,047–88,196,488, 1,442 basesExon 11: 88,197,669–88,197,765, 97 basesExon 10: 88,198,976–88,199,150, 175 basesExon 9: 88,202,962–88,203,075, 114 basesExon 8: 88,205,814–88,205,954, 141 basesExon 7: 88,206,439–88,206,499, 61 basesExon 6: 88,207,029–88,207,180, 152 basesExon 5: 88,220,563–88,220,719, 157 basesExon 4: 88,225,769–88,225,866, 98 basesExon 3: 88,228,445–88,228,528, 84 basesExon 2: 88,240,813–88,240,916, 104 basesExon 1: 88,268,721–88,268,845, 125 bases1210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.8 kb of the gene's 73.8 kb; 1,464 of those bases code for the protein.

Sequencing TMEM161B

33Moderate

How hard TMEM161B is to sequence with short reads, out of 100

Some of TMEM161B's exons sit where short reads can miss or misplace a change.

What adds to it: the share of TMEM161B's exons in each kind of hard region

  • Mappability1.5%
  • Homology47%
  • Shared with chrY0%
  • Reference coverage0%
  • Repeats4.4%
  • GC content20%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). TMEM161B gene: transmembrane protein 161B. Retrieved 21 October 2026, from https://dantelabs.com/genes/tmem161b

Vancouver

Dante Labs. TMEM161B gene: transmembrane protein 161B [Internet]. [cited 21 October 2026]. Available from: https://dantelabs.com/genes/tmem161b

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