Skip to content
Use your HSA or FSA funds

Gene

TFF3

trefoil factor 3

Summary

Cytogenetic location
21q22.3
Coordinates
Chromosome 21: 42,311,667–42,315,409 (GRCh38)
Exons
3 exons across 3.7 kb
Protein
80 amino acids
Also known as
HITF, ITF
MANE Select transcript
ENST00000518498.3NM_003226.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TFF3 yet. The test sequences your whole genome, so your data includes it all the same.

How TFF3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 21, with a bracket where TFF3 sits. TFF3 and 12 genes near it on chromosome 21, from 41,813,538 to 42,813,537.Chromosome 2121q22.3p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.342 Mb42.2 Mb42.4 Mb42.6 Mb42.8 MbPRDM15: 41,798,225–41,879,482, reverse strandPRDM15C2CD2: 41,885,111–41,954,022, reverse strandC2CD2ZBTB21: 41,986,293–42,010,387, reverse strandZBTB21UMODL1: 42,062,959–42,143,453, forward strandUMODL1ABCG1: 42,199,689–42,304,389, forward strandABCG1TFF3: 42,311,667–42,315,409, reverse strandTFF3TFF2: 42,346,357–42,350,997, reverse strandTFF2TFF1: 42,362,282–42,366,541, reverse strandTFF1TMPRSS3: 42,371,840–42,396,122, reverse strandTMPRSS3UBASH3A: 42,403,447–42,447,684, forward strandUBASH3ARSPH1: 42,472,486–42,496,366, reverse strandRSPH1SLC37A1: 42,495,994–42,581,440, forward strandSLC37A1PDE9A: 42,653,584–42,776,512, forward strandPDE9ADiagram of TFF3: 3 exons on the reverse strand of chromosome 21Exon 3: 42,311,667–42,312,269, 603 basesExon 2: 42,313,485–42,313,631, 147 basesExon 1: 42,315,293–42,315,409, 117 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.9 kb of the gene's 3.7 kb; 243 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TFF3 gene: trefoil factor 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/tff3

Vancouver

Dante Labs. TFF3 gene: trefoil factor 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tff3

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test