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Gene

SPRY1

sprouty RTK signaling antagonist 1

Summary

Cytogenetic location
4q28.1
Coordinates
Chromosome 4: 123,396,795–123,403,755 (GRCh38)
Exons
3 exons across 7 kb
Protein
319 amino acids
Also known as
hSPRY1
MANE Select transcript
ENST00000651917.1NM_001258038.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SPRY1 yet. The test sequences your whole genome, so your data includes it all the same.

How SPRY1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 4, with a bracket where SPRY1 sits. SPRY1 and 2 genes near it on chromosome 4, from 122,900,275 to 123,900,274.Chromosome 44q28.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.2123 Mb123.2 Mb123.4 Mb123.6 Mb123.8 MbNUDT6: 122,886,565–122,922,968, reverse strandNUDT6AFG2A: 122,923,070–123,319,433, forward strandAFG2ASPRY1: 123,396,795–123,403,755, forward strandSPRY1Diagram of SPRY1: 3 exons on the forward strand of chromosome 4Exon 1: 123,396,795–123,396,932, 138 basesExon 2: 123,397,611–123,397,856, 246 basesExon 3: 123,401,537–123,403,755, 2,219 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 7 kb; 960 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SPRY1 gene: sprouty RTK signaling antagonist 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/spry1

Vancouver

Dante Labs. SPRY1 gene: sprouty RTK signaling antagonist 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/spry1

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