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Gene

SMAD1

SMAD family member 1

Summary

Cytogenetic location
4q31.21
Coordinates
Chromosome 4: 145,481,853–145,559,176 (GRCh38)
Exons
7 exons across 77.3 kb
Protein
465 amino acids
Also known as
MADR1, JV4-1
Previous symbols
MADH1
MANE Select transcript
ENST00000302085.9NM_005900.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMAD1 yet. The test sequences your whole genome, so your data includes it all the same.

How SMAD1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where SMAD1 sits. SMAD1 and 7 genes near it on chromosome 4, from 145,020,515 to 146,020,514.Chromosome 44q31.21p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.2145.2 Mb145.4 Mb145.6 Mb145.8 Mb146 Mb: 144,210,701–145,098,174, reverse strandANAPC10: 144,831,908–145,098,823, reverse strandANAPC10ABCE1: 145,098,248–145,131,334, forward strandABCE1OTUD4: 145,110,838–145,180,631, reverse strandOTUD4SMAD1: 145,481,853–145,559,176, forward strandSMAD1MMAA: 145,599,042–145,660,033, forward strandMMAAC4orf51: 145,680,088–145,771,032, forward strandC4orf51ZNF827: 145,757,627–145,939,036, reverse strandZNF827Diagram of SMAD1: 7 exons on the forward strand of chromosome 4Exon 1: 145,481,853–145,482,038, 186 basesExon 2: 145,514,438–145,515,013, 576 basesExon 3: 145,539,804–145,540,061, 258 basesExon 4: 145,542,582–145,542,698, 117 basesExon 5: 145,546,703–145,546,924, 222 basesExon 6: 145,553,784–145,554,040, 257 basesExon 7: 145,557,791–145,559,176, 1,386 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3 kb of the gene's 77.3 kb; 1,398 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SMAD1 gene: SMAD family member 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/smad1

Vancouver

Dante Labs. SMAD1 gene: SMAD family member 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smad1

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