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Gene

PRAME

PRAME nuclear receptor transcriptional regulator

Summary

Cytogenetic location
22q11.22
Coordinates
Chromosome 22: 22,547,701–22,559,265 (GRCh38)
Exons
6 exons across 11.6 kb
Protein
509 amino acids
Also known as
CT130
Previous symbols
MAPE
MANE Select transcript
ENST00000405655.8NM_206956.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PRAME yet. The test sequences your whole genome, so your data includes it all the same.

How PRAME is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where PRAME sits. PRAME and 5 genes near it on chromosome 22, from 22,053,483 to 23,053,482.Chromosome 2222q11.22p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3322.2 Mb22.4 Mb22.6 Mb22.8 Mb23 MbVPREB1: 22,244,780–22,245,515, forward strandVPREB1ZNF280B: 22,484,421–22,508,815, reverse strandZNF280BZNF280A: 22,513,226–22,520,273, reverse strandZNF280APRAME: 22,547,701–22,559,265, reverse strandPRAMEGGTLC2: 22,644,614–22,647,898, forward strandGGTLC2IGLL5: 22,887,780–22,896,111, forward strandIGLL5Diagram of PRAME: 6 exons on the reverse strand of chromosome 22Exon 6: 22,547,701–22,548,643, 943 basesExon 5: 22,549,726–22,550,334, 609 basesExon 4: 22,550,767–22,551,089, 323 basesExon 3: 22,556,812–22,556,909, 98 basesExon 2: 22,557,545–22,557,580, 36 basesExon 1: 22,558,971–22,559,265, 295 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.3 kb of the gene's 11.6 kb; 1,530 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PRAME gene: PRAME nuclear receptor transcriptional regulator. Retrieved 17 October 2026, from https://dantelabs.com/genes/prame

Vancouver

Dante Labs. PRAME gene: PRAME nuclear receptor transcriptional regulator [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/prame

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