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Gene

PON1

paraoxonase 1

Summary

Cytogenetic location
7q21.3
Coordinates
Chromosome 7: 95,297,676–95,324,532 (GRCh38)
Exons
9 exons across 26.9 kb
Protein
355 amino acids
Also known as
ESA
Previous symbols
PON
MANE Select transcript
ENST00000222381.8NM_000446.7
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PON1 yet. The test sequences your whole genome, so your data includes it all the same.

How PON1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where PON1 sits. PON1 and 6 genes near it on chromosome 7, from 94,811,104 to 95,811,103.Chromosome 77q21.3p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.395 Mb95.2 Mb95.4 Mb95.6 Mb95.8 MbPPP1R9A: 94,907,202–95,296,415, forward strandPPP1R9APON1: 95,297,676–95,324,532, reverse strandPON1PON3: 95,357,618–95,396,493, reverse strandPON3PON2: 95,403,733–95,435,393, reverse strandPON2ASB4: 95,478,444–95,540,233, forward strandASB4PDK4: 95,583,497–95,597,638, reverse strandPDK4DYNC1I1: 95,772,459–96,110,915, forward strandDYNC1I1Diagram of PON1: 9 exons on the reverse strand of chromosome 7Exon 9: 95,297,676–95,299,102, 1,427 basesExon 8: 95,302,205–95,302,333, 129 basesExon 7: 95,306,285–95,306,366, 82 basesExon 6: 95,308,011–95,308,211, 201 basesExon 5: 95,311,451–95,311,577, 127 basesExon 4: 95,315,322–95,315,490, 169 basesExon 3: 95,316,734–95,316,789, 56 basesExon 2: 95,318,323–95,318,393, 71 basesExon 1: 95,324,402–95,324,532, 131 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 26.9 kb; 1,068 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PON1 gene: paraoxonase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/pon1

Vancouver

Dante Labs. PON1 gene: paraoxonase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pon1

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