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Gene

PNPLA5

patatin like domain 5, triacylglycerol lipase

Summary

Cytogenetic location
22q13.31
Coordinates
Chromosome 22: 43,879,678–43,892,013 (GRCh38)
Exons
9 exons across 12.3 kb
Protein
429 amino acids
Also known as
dJ388M5.4, GS2L
MANE Select transcript
ENST00000216177.9NM_138814.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PNPLA5 yet. The test sequences your whole genome, so your data includes it all the same.

How PNPLA5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 22, with a bracket where PNPLA5 sits. PNPLA5 and 8 genes near it on chromosome 22, from 43,385,846 to 44,385,845.Chromosome 2222q13.31p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3343.4 Mb43.6 Mb43.8 Mb44 Mb44.2 MbMPPED1: 43,411,196–43,507,850, forward strandMPPED1EFCAB6: 43,528,744–43,812,337, reverse strandEFCAB6SULT4A1: 43,824,507–43,862,545, reverse strandSULT4A1PNPLA5: 43,879,678–43,892,013, reverse strandPNPLA5PNPLA3: 43,923,761–43,964,488, forward strandPNPLA3SAMM50: 43,955,399–44,010,531, forward strandSAMM50PARVB: 43,999,211–44,172,939, forward strandPARVBPARVG: 44,172,946–44,219,533, forward strandPARVGSHISAL1: 44,243,665–44,332,009, reverse strandSHISAL1Diagram of PNPLA5: 9 exons on the reverse strand of chromosome 22Exon 9: 43,879,678–43,880,885, 1,208 basesExon 8: 43,881,558–43,881,674, 117 basesExon 7: 43,884,213–43,884,345, 133 basesExon 6: 43,886,303–43,886,488, 186 basesExon 5: 43,887,591–43,887,651, 61 basesExon 4: 43,889,329–43,889,538, 210 basesExon 3: 43,889,799–43,889,864, 66 basesExon 2: 43,891,062–43,891,294, 233 basesExon 1: 43,891,688–43,892,013, 326 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 12.3 kb; 1,290 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PNPLA5 gene: patatin like domain 5, triacylglycerol lipase. Retrieved 17 October 2026, from https://dantelabs.com/genes/pnpla5

Vancouver

Dante Labs. PNPLA5 gene: patatin like domain 5, triacylglycerol lipase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pnpla5

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