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Gene

OSBPL8

oxysterol binding protein like 8

Summary

Cytogenetic location
12q21.2
Coordinates
Chromosome 12: 76,351,797–76,559,771 (GRCh38)
Exons
24 exons across 208 kb
Protein
889 amino acids
Also known as
OSBP10, ORP8, MST120, MSTP120
MANE Select transcript
ENST00000261183.8NM_020841.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads OSBPL8 yet. The test sequences your whole genome, so your data includes it all the same.

How OSBPL8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where OSBPL8 sits. OSBPL8 and 5 genes near it on chromosome 12, from 75,955,784 to 76,955,783.Chromosome 1212q21.2p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3376 Mb76.2 Mb76.4 Mb76.6 Mb76.8 MbPHLDA1: 76,025,447–76,032,560, reverse strandPHLDA1NAP1L1: 76,032,987–76,085,624, reverse strandNAP1L1BBS10: 76,344,474–76,348,447, reverse strandBBS10OSBPL8: 76,351,797–76,559,771, reverse strandOSBPL8ZDHHC17: 76,763,993–76,853,940, forward strandZDHHC17CSRP2: 76,843,865–76,879,638, reverse strandCSRP2Diagram of OSBPL8: 24 exons on the reverse strand of chromosome 12Exon 24: 76,351,797–76,356,021, 4,225 basesExon 23: 76,356,626–76,356,728, 103 basesExon 22: 76,358,706–76,358,811, 106 basesExon 21: 76,369,214–76,369,301, 88 basesExon 20: 76,369,637–76,369,822, 186 basesExon 19: 76,371,448–76,371,584, 137 basesExon 18: 76,373,344–76,373,433, 90 basesExon 17: 76,375,273–76,375,370, 98 basesExon 16: 76,378,452–76,378,550, 99 basesExon 15: 76,384,254–76,384,350, 97 basesExon 14: 76,386,168–76,386,266, 99 basesExon 13: 76,386,579–76,386,660, 82 basesExon 12: 76,389,645–76,389,829, 185 basesExon 11: 76,390,420–76,390,657, 238 basesExon 10: 76,392,581–76,392,752, 172 basesExon 9: 76,394,645–76,394,729, 85 basesExon 8: 76,397,694–76,397,897, 204 basesExon 7: 76,399,873–76,399,974, 102 basesExon 6: 76,402,689–76,402,766, 78 basesExon 5: 76,410,564–76,410,634, 71 basesExon 4: 76,450,851–76,450,988, 138 basesExon 3: 76,459,859–76,459,895, 37 basesExon 2: 76,487,510–76,487,618, 109 basesExon 1: 76,559,397–76,559,771, 375 bases24201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.2 kb of the gene's 208 kb; 2,670 of those bases code for the protein.

How a genome test reads OSBPL8

1

position in OSBPL8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 208 kb of OSBPL8, introns included, not only the 7.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). OSBPL8 gene: oxysterol binding protein like 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/osbpl8

Vancouver

Dante Labs. OSBPL8 gene: oxysterol binding protein like 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/osbpl8

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