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Gene

NUMB

NUMB endocytic adaptor protein

Summary

Cytogenetic location
14q24.3
Coordinates
Chromosome 14: 73,275,216–73,458,546 (GRCh38)
Exons
13 exons across 183.3 kb
Protein
651 amino acids
Previous symbols
C14orf41
MANE Select transcript
ENST00000555238.6NM_001005743.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NUMB yet. The test sequences your whole genome, so your data includes it all the same.

How NUMB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 14, with a bracket where NUMB sits. NUMB and 17 genes near it on chromosome 14, from 72,866,881 to 73,866,880.Chromosome 1414q24.3p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3373 Mb73.2 Mb73.4 Mb73.6 Mb73.8 MbDPF3: 72,609,034–72,894,117, reverse strandDPF3DCAF4: 72,926,358–72,962,098, forward strandDCAF4ZFYVE1: 72,969,445–73,027,140, reverse strandZFYVE1RBM25: 73,058,307–73,123,899, forward strandRBM25PSEN1: 73,136,418–73,223,691, forward strandPSEN1PAPLN: 73,236,338–73,345,508, forward strandPAPLNNUMB: 73,275,216–73,458,546, reverse strandNUMBHEATR4: 73,478,484–73,558,947, reverse strandHEATR4RIOX1: 73,490,933–73,520,134, forward strandRIOX1ACOT1: 73,537,122–73,543,797, forward strandACOT1ACOT2: 73,567,620–73,588,885, forward strandACOT2ACOT4: 73,591,660–73,595,766, forward strandACOT4ACOT6: 73,610,945–73,619,888, forward strandACOT6DNAL1: 73,644,875–73,703,732, forward strandDNAL1PNMA1: 73,711,783–73,714,384, reverse strandPNMA1MIDEAS: 73,715,122–73,790,285, reverse strandMIDEASPTGR2: 73,851,792–73,885,726, forward strandPTGR2: 73,851,971–73,932,278, forward strandDiagram of NUMB: 13 exons on the reverse strand of chromosome 14Exon 13: 73,275,216–73,277,293, 2,078 basesExon 12: 73,279,281–73,279,424, 144 basesExon 11: 73,282,359–73,282,505, 147 basesExon 10: 73,284,081–73,284,374, 294 basesExon 9: 73,287,110–73,287,314, 205 basesExon 8: 73,292,734–73,292,874, 141 basesExon 7: 73,297,211–73,297,285, 75 basesExon 6: 73,316,390–73,316,422, 33 basesExon 5: 73,323,130–73,323,204, 75 basesExon 4: 73,355,626–73,355,766, 141 basesExon 3: 73,366,897–73,366,981, 85 basesExon 2: 73,409,937–73,410,068, 132 basesExon 1: 73,458,493–73,458,546, 54 bases1310515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.6 kb of the gene's 183.3 kb; 1,956 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). NUMB gene: NUMB endocytic adaptor protein. Retrieved 16 October 2026, from https://dantelabs.com/genes/numb

Vancouver

Dante Labs. NUMB gene: NUMB endocytic adaptor protein [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/numb

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