Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

MAPK8

mitogen-activated protein kinase 8

Summary

Cytogenetic location
10q11.22
Coordinates
Chromosome 10: 48,306,677–48,439,360 (GRCh38)
Exons
12 exons across 132.7 kb
Protein
427 amino acids
Also known as
JNK, JNK1, SAPK1
Previous symbols
PRKM8
MANE Select transcript
ENST00000374189.6NM_001323329.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads MAPK8 yet. The test sequences your whole genome, so your data includes it all the same.

How MAPK8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 10, with a bracket where MAPK8 sits. MAPK8 and 5 genes near it on chromosome 10, from 47,873,019 to 48,873,018.Chromosome 1010q11.22p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.348 Mb48.2 Mb48.4 Mb48.6 Mb48.8 MbNPY4R2: 47,918,662–47,925,736, forward strandNPY4R2FAM25C: 47,995,320–47,999,796, reverse strandFAM25CFRMPD2: 48,153,088–48,274,913, reverse strandFRMPD2MAPK8: 48,306,677–48,439,360, forward strandMAPK8ARHGAP22: 48,429,882–48,656,265, reverse strandARHGAP22WDFY4: 48,684,825–48,982,959, forward strandWDFY4Diagram of MAPK8: 12 exons on the forward strand of chromosome 10Exon 1: 48,306,677–48,306,821, 145 basesExon 2: 48,401,612–48,401,782, 171 basesExon 3: 48,404,852–48,404,981, 130 basesExon 4: 48,409,879–48,409,937, 59 basesExon 5: 48,410,030–48,410,168, 139 basesExon 6: 48,420,155–48,420,320, 166 basesExon 7: 48,424,088–48,424,159, 72 basesExon 8: 48,425,888–48,426,070, 183 basesExon 9: 48,426,380–48,426,504, 125 basesExon 10: 48,427,080–48,427,143, 64 basesExon 11: 48,431,193–48,431,270, 78 basesExon 12: 48,434,884–48,439,360, 4,477 bases1510125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.8 kb of the gene's 132.7 kb; 1,284 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAPK8 gene: mitogen-activated protein kinase 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/mapk8

Vancouver

Dante Labs. MAPK8 gene: mitogen-activated protein kinase 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mapk8

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test